
Tri Clamp Envelope Gasket PTFE (Teflon) X EPDM Sanitary Pharmaceutical Grade
- PTFE + EPDM envelope inhibits creep & cold flow
- 21CFR177.2600 compliant, GMP-grade material
- 10-year shelf life, sizes up to 12 inch
ISO 9001 Approved
FDA 21 CFR 177.2600
GMP Compliant
EPDM PTFE gaskets from Artesian Systems combine the broad chemical resistance of PTFE with the sealing memory and elasticity of EPDM elastomer. Available in envelope and unitized designs, these FDA 21 CFR 177.2600 compliant gaskets are engineered for sanitary, pharmaceutical, food and beverage, and chemical processing applications in sizes up to 12 inches.




EPDM gaskets are rubber-based elastomers offering excellent sealing memory, elasticity, and temperature resilience but limited chemical resistance. PTFE gaskets provide broad chemical resistance and a non-stick surface but are prone to creep and cold flow. EPDM PTFE envelope gaskets combine both materials — using PTFE as the sealing surface and EPDM as the elastic core — delivering the strengths of each material.
Talk to our experts for custom solutions and tailored guidance.

FDA 21 CFR 177.2600 and GMP-compliant gaskets for drug manufacturing and biotech fluid handling systems.

Sanitary-grade PTFE x EPDM gaskets meeting FDA and USDA compliance for food-contact pipeline connections.

Broad chemical resistance of PTFE sealing surface protects against aggressive media in chemical production systems.

Chemically resistant, GMP-compliant gaskets for nutraceutical, hemp oil, and botanical extraction systems.
Talk to our experts for custom solutions and tailored guidance.
Artesian Systems was founded by a mechanical engineer with almost 20 years in petroleum, chemical, and food industries, ensuring application-specific gasket solutions.
All EPDM PTFE gaskets meet FDA 21 CFR 177.2600, USDA, and GMP standards — reducing compliance risk in food, pharma, and biotech production environments.
Dual-material construction combats creep, cold flow, and leakage, offering longer service intervals and fewer process interruptions than standard PTFE-only gaskets.
Submit your requirements and our engineering team will respond with expert guidance on sizing, compliance, and application fit.
For immediate assistance, feel free to give us a direct call at +(801) 318 – 4079. You can also send us a quick email at artesiansystems@gmail.com.
For immediate assistance, feel free to give us a direct call at +(801) 318 – 4079. You can also send us a quick email at artesiansystems@gmail.com.