ISO 9001 Approved certified

ISO 9001 Approved

FDA 21 CFR 177.2600 certified

FDA 21 CFR 177.2600

GMP compliant certified

GMP Compliant

EPDM PTFE Gaskets

EPDM PTFE gaskets from Artesian Systems combine the broad chemical resistance of PTFE with the sealing memory and elasticity of EPDM elastomer. Available in envelope and unitized designs, these FDA 21 CFR 177.2600 compliant gaskets are engineered for sanitary, pharmaceutical, food and beverage, and chemical processing applications in sizes up to 12 inches.

Tri Clamp Envelope Gasket PTFE (Teflon) X EPDM Sanitary Pharmaceutical Grade
Tri Clamp Unitized Gasket PTFE (Teflon) x EPDM Sanitary Pharmaceutical Grade

Our Range of Products

Tri Clamp Envelope Gasket PTFE (Teflon) X EPDM Sanitary Pharmaceutical Grade

Tri Clamp Envelope Gasket PTFE (Teflon) X EPDM Sanitary Pharmaceutical Grade

  • PTFE + EPDM envelope inhibits creep & cold flow
  • 21CFR177.2600 compliant, GMP-grade material
  • 10-year shelf life, sizes up to 12 inch
Tri Clamp Unitized Gasket PTFE (Teflon) x EPDM Sanitary Pharmaceutical Grade

Tri Clamp Unitized Gasket PTFE (Teflon) x EPDM Sanitary Pharmaceutical Grade

  • One-piece unitized design for stable sealing
  • FDA 21 CFR 177.2600 & GMP compatible
  • PTFE surface with EPDM core, 10-yr shelf life

Frequently Asked Questions

What is the difference between EPDM and PTFE gaskets?

EPDM gaskets are rubber-based elastomers offering excellent sealing memory, elasticity, and temperature resilience but limited chemical resistance. PTFE gaskets provide broad chemical resistance and a non-stick surface but are prone to creep and cold flow. EPDM PTFE envelope gaskets combine both materials — using PTFE as the sealing surface and EPDM as the elastic core — delivering the strengths of each material.

What is EPDM in gasket?

What is a PTFE gasket?

What sizes are available for EPDM PTFE gaskets?

Are EPDM PTFE gaskets FDA compliant?

What is the difference between envelope and unitized EPDM PTFE gaskets?

What is the shelf life and storage requirement for these gaskets?

Didn't find what you're looking for?

Talk to our experts for custom solutions and tailored guidance.

Industries We Serve

Pharmaceutical & Biotechnology

Pharmaceutical & Biotechnology

FDA 21 CFR 177.2600 and GMP-compliant gaskets for drug manufacturing and biotech fluid handling systems.

Food & Beverage Processing

Food & Beverage Processing

Sanitary-grade PTFE x EPDM gaskets meeting FDA and USDA compliance for food-contact pipeline connections.

Chemical Processing

Chemical Processing

Broad chemical resistance of PTFE sealing surface protects against aggressive media in chemical production systems.

Nutraceutical & Hemp Extraction

Nutraceutical & Hemp Extraction

Chemically resistant, GMP-compliant gaskets for nutraceutical, hemp oil, and botanical extraction systems.

Didn't find what you're looking for?

Talk to our experts for custom solutions and tailored guidance.

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Why Pharma & Food Engineers Choose Artesian Systems

Nearly Two Decades of Industry Expertise

Artesian Systems was founded by a mechanical engineer with almost 20 years in petroleum, chemical, and food industries, ensuring application-specific gasket solutions.

FDA & GMP Regulatory Compliance

All EPDM PTFE gaskets meet FDA 21 CFR 177.2600, USDA, and GMP standards — reducing compliance risk in food, pharma, and biotech production environments.

Engineered for Superior Sealing Performance

Dual-material construction combats creep, cold flow, and leakage, offering longer service intervals and fewer process interruptions than standard PTFE-only gaskets.

Need Help Selecting the Right EPDM PTFE Gasket?

Submit your requirements and our engineering team will respond with expert guidance on sizing, compliance, and application fit.

Contact Us Today

For immediate assistance, feel free to give us a direct call at +(801) 318 – 4079. You can also send us a quick email at artesiansystems@gmail.com.