PTFE Unitized Tri Clamp Gaskets — Pharmaceutical Grade

An envelope gasket wraps a PTFE outer layer around a filler core, while a unitized gasket bonds the PTFE sealing surface directly to an EPDM elastomer core into a single one-piece assembly. The unitized design reduces component movement, improves installation stability, and minimizes the risk of misalignment during assembly compared to the envelope construction.

Yes. Both the envelope and unitized PTFE tri clamp gaskets from Artesian Systems comply with FDA 21 CFR 177.2600. They are also compatible with GMP (Good Manufacturing Practices) regulated systems and meet 3A and USDA material standards, making them suitable for pharmaceutical, food processing, and biotechnology applications.

These gaskets are available in eight sizes: 1.5", 2", 3", 4", 6", 8", 10", and 12". Pricing starts at $21.00 and varies by size. The unitized design accommodates standard tri-clamp sanitary ferrule connections across this full size range.

These gaskets have a shelf life of 10 years from the cure date. They should be stored in original packaging in a clean, dry environment at 65°F to 85°F, away from direct sunlight and at least 6 feet from electric motors to prevent ozone degradation of the EPDM core.

No. These PTFE unitized and envelope gaskets are designed specifically for sanitary tri-clamp connections and are not recommended for use with bolted clamp assemblies. Additionally, the 150 PSI sanitary clamp service rating does not apply to connections 1" and larger when using any PTFE-based gaskets due to potential cold flow under high clamping loads.

Solid PTFE gaskets are prone to creep, cold flow, and poor sealing recovery under pressure cycling. The PTFE-EPDM combination addresses these drawbacks by using PTFE as the chemical-resistant contact surface while the EPDM core provides sealing memory and elasticity. This results in more reliable long-term sealing, especially where minor ferrule misalignment exists.